
Exosome Therapy by BENEV®
A growing number of patients want firmer, clearer, more refreshed skin without surgery or extended downtime. Regenerative skin care has answered that demand, and exosomes sit at the front of the conversation. At Terrasse Aesthetic Surgery and ERASE MediSpa, we use Exosome Regenerative Complex by BENEV to support your skin’s own repair machinery, whether on its own or as a finishing layer that amplifies your laser and microneedling results.
If you have been curious about the regenerative treatments your favorite aesthetic clinics keep talking about, here is a clear, honest look at what exosomes are, what they do and how Dr. Anthony Terrasse and our licensed medical aestheticians put them to work for you.
What Are Exosomes?
Exosomes are tiny vesicles that your cells naturally release to communicate with one another. Measuring roughly 30 to 200 nanometers, they shuttle growth factors, peptides, messenger RNA and other signaling molecules between cells, including the fibroblasts and keratinocytes responsible for healthy, resilient skin. Think of them as the messengers that tell your skin cells when to repair, rebuild and regenerate.
BENEV Exosome Regenerative Complex delivers stem cell-derived, lyophilized (freeze-dried) exosomes alongside growth factors, peptides, coenzymes, amino acids, hyaluronic acid, vitamins and minerals. The product arrives in a dual-vial system that your provider mixes fresh right before application, then applies topically to your skin. There are no blood draws and no donor injections involved, which sets it apart from platelet-rich plasma (PRP).
One detail we appreciate as a practice: BENEV partners with exosome research company ExoCoBio, and the formulation is paraben-free, steroid-free and hypoallergenic. Quality and sourcing matter a great deal in this category, and BENEV remains one of the more rigorously studied options available.

What Can Exosome Therapy Address?
Exosome therapy works beneath the surface to improve overall skin quality rather than addressing a single flaw. Patients typically pursue it to soften the look of fine lines, calm redness, even out tone and restore a healthier glow. Because the treatment supports your skin’s repair response, it can help with several concerns at once, including:
- Fine lines and early wrinkles: Growth factor signaling encourages new collagen, which helps smooth texture over time.
- Dullness and uneven tone: Exosomes support cellular renewal for a brighter, more refreshed complexion.
- Redness and post-procedure inflammation: Their calming, anti-inflammatory effect helps quiet irritated skin.
- Loss of firmness and elasticity: Regenerative signaling supports the structural proteins that keep skin supple.
- Slow recovery after laser or microneedling: Applied immediately afterward, exosomes can speed healing and reduce downtime.
A quick note on expectations: BENEV Exosome products are cosmetic topical solutions, not drugs, and they are not intended to treat or cure any medical condition. What they do well is support healthier-looking, better-functioning skin.
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Schedule NowCan Exosomes Be a Standalone Treatment?
Yes. While many patients add exosomes to another treatment, exosome therapy can also stand on its own as a regenerative facial that refreshes and revitalizes your complexion with very little downtime. This standalone option appeals to patients who want a gentle, regenerative boost or who are addressing early changes in skin quality before they consider more involved procedures.
That said, exosomes shine brightest when paired with a treatment that creates micro-channels in the skin. Procedures like Vivace RF microneedling, MOXI, BBL HERO and CoolPeel CO2 resurfacing open temporary pathways that let the exosome complex penetrate more deeply, right when your skin is most receptive to regenerative signals. During your consultation, Dr. Terrasse or your aesthetician will recommend whether a standalone session or a combination approach makes the most sense for your goals.
“Exosomes don’t replace a great laser or microneedling treatment. They make a good result even better by supporting your skin’s own repair process at the cellular level.” — Dr. Anthony Terrasse
Who Is a Good Candidate for Exosome Therapy?
Exosome therapy suits a wide range of patients because it is gentle, topical and safe for all skin types and tones. You may be a good candidate if you want to improve skin texture, tone and firmness, if you are looking for a regenerative alternative to PRP, or if you want to enhance and speed recovery from a resurfacing treatment.
Good candidates for exosome therapy are generally in good overall health, have realistic expectations about gradual improvement and want a minimally invasive approach to skin quality. Patients with active skin infections or certain medical conditions may need to wait or pursue another option, so a consultation is the best way to confirm this treatment is right for you. Since exosomes are applied topically and do not affect muscle or nerve activity, they fit comfortably alongside injectables and other treatments in a broader plan.
How to Prepare for Exosome Therapy
Preparation is straightforward, especially for a standalone session. Arrive with clean skin, free of makeup, heavy lotions and sunscreen. In the days leading up to your appointment, protect your skin from excess sun exposure and avoid harsh actives like retinoids or strong exfoliating acids, which can leave your skin more sensitive.
If you are combining exosomes with microneedling or a laser treatment, follow the prep instructions for that procedure, since those guidelines take priority. That usually means pausing blood-thinning medications and supplements such as aspirin, vitamin E and fish oil for a couple of weeks beforehand, with your provider’s guidance. Dr. Terrasse will give you specifics based on your treatment plan and health history.
What to Expect During Exosome Treatment
Here is how a typical exosome session unfolds at our Lake Forest office:
- Cleansing: Your provider thoroughly cleanses and dries the treatment area.
- Channel creation (for combination treatments): If exosomes are paired with microneedling or a laser, that procedure is performed first to create micro-channels in the skin.
- Mixing the complex: The lyophilized exosome vial is combined with its diluent and mixed fresh, since the product is most effective when applied right after reconstitution.
- Application: The exosome complex is applied across the treatment area and absorbs into the skin, delivering its concentrated signaling molecules where they can do the most work.
- Finishing: A soothing product may be applied, and you will receive simple aftercare guidance.
A standalone session is quick and comfortable, often completed in well under an hour. Combination treatments take longer depending on the paired procedure.
What Is Recovery Like After Exosome Therapy?
One of the biggest draws of exosome therapy is how little downtime it requires. On its own, the treatment involves minimal recovery, and most patients return to normal activities right away. You might notice mild redness, which typically settles within a few hours.
When exosomes follow a resurfacing treatment, they actively help your skin heal. By supporting your natural repair process and calming inflammation, they can shorten the recovery period and reduce redness compared to the laser or microneedling treatment alone. For combination sessions, follow the aftercare for your primary procedure, protect your skin from the sun and apply a broad-spectrum SPF of 30 or higher while your skin recovers.
What Results Can I Expect From Exosome Therapy?
Many patients notice an immediate freshness to their skin after the first session, with texture and radiance continuing to improve as the regenerative process unfolds over the following weeks. BENEV’s clinical work reported that participants saw a noticeable difference after their first treatment, with fuller results developing after three to five sessions.
The science behind combining exosomes with microneedling is increasingly compelling. In a split-face study reviewed in the Journal of Cosmetic Dermatology, skin elasticity improved by an average of 11.3% on the side treated with exosomes plus microneedling, while the microneedling-only side saw a 3.3% decline over 12 weeks. A 2026 systematic review of microneedling with exosomes found greater collagen density and new collagen synthesis on the exosome-treated side compared with microneedling alone, supporting what we see clinically: exosomes help your skin build a better result.
Results vary from person to person, and they are not permanent. Periodic maintenance sessions help sustain your improvements as your skin continues to age. Pairing your treatments with a thoughtful, medical-grade skincare routine will help protect and extend everything you gain.
Give Your Skin a Better Set of Instructions in Lake Forest, IL
Whether you want a standalone regenerative refresh or a finishing layer that gets more out of your microneedling or laser treatment, exosome therapy by BENEV offers a science-backed way to support healthier, clearer skin. Board-certified plastic surgeon Dr. Anthony Terrasse, recognized as a “Top Doctor” by U.S. News & World Report, and our licensed medical aestheticians will help you decide how exosomes fit into your plan.
Call 847-234-2400 or contact us online to schedule your consultation at Terrasse Aesthetic Surgery and ERASE MediSpa in Lake Forest, IL.


